DiPha – a tool for prediction and guidance of purposeful pharmacotherapy

Medical doctors currently prescribe a number of medicinal products, while scientific studies describe that the drugs are effective in only 60% of patients and also a significant number of patients are hospitalized for the occurrence of serious side effects after applied pharmacotherapy. Genetic factors, i.e. information stored in our DNA, are proven to play a key role in the reaction to drugs. Pharmacogenomics is a field that studies the influence of the patient’s genetics predisposition to the drug’s effectiveness and, on the other hand, to the occurrence of adverse effects. The result of the pharmacogenetic examination affects the choice of a drugs dosage according to the genetic profile of individual patients. With the significantly increasing number of prescribed drugs, the need to boost the capacity of examinations that determine the genetic factors influencing the effects of drugs is also increasing, as weel as requirement to improve the implementation of the results of these examinations into clinical practice leading to correct treatment decisions. A possible way to improve accessibility is the screening genetic testing, when collected comprehensive pharmacogenomic information and are readily available for future drug prescribing decisions.

Official press release available here.

CZ.01.01.01/01/22_002/0000717 DiPha